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Friday, April 24, 2020

Corona vaccine trial begins in humans


According to the details, Oxford University has started testing the corona vaccine in the United Kingdom.

This is the first trial of the corona vaccine on humans in Europe, although the United States has already started testing the corona vaccine on humans in March.

According to a report by the British Broadcasting Corporation, the vaccine developed by the scientists of Oxford University was given to two volunteers by injection.

Oxford solicited applications from people aged 18 to 55 to join the trial program, after which 800 volunteers were selected, one of whom was vaccinated today, a woman and a man.

Under the program, half of the volunteers will be vaccinated against the corona virus and the other half will be vaccinated against meningitis instead of corona. However, the volunteers will not know which vaccine they have been given. It will be recorded.

Alyssa Granato is the first European volunteer to be vaccinated against coronavirus and she is a scientist herself. She says she is a scientist herself so she wanted to be part of this scientific process.

The vaccine was developed by a team led by Oxford University professor Sarah Gilbert in a short span of three months and she says she personally has high hopes for the vaccine.

How was the vaccine developed?
In the development of this vaccine, a group of weak viruses that cause the common cold in humans (adenovirus, a group of double-stranded DNA viruses that cause respiratory problems in mammals, such as the common cold, etc.) However, it was genetically modified so that it could enter the human body and grow.

The Oxford team has previously developed vaccines for coronavirus-like viruses such as Middle East Respiratory Syndrome (MERS) using the same method, and clinical trials have shown encouraging results.

How do you know if the vaccine is working?
The only way to know if the vaccine is working is to keep up with the current wave of corona viruses in the UK, as scientists look at the number of people infected with the virus and the proportion of people recovering from the vaccine in the coming months. And if the number of cases of the virus suddenly drops in the UK, then it will be difficult to know whether the vaccine is effective or not.

Due to the low number of cases, scientists will not have enough data for comparative analysis.

Professor Andrew Pollard, director of the Oxford Vaccine Group, said: "We are trying to determine the end of the current wave of epidemics. There are likely to be more cases of corona in the future as the virus is not yet completely eradicated.

Experts are preferring health workers for this trial because medical personnel are more likely to be infected with corona than other people.

A separate trial of 5,000 people will also begin soon, with no age limit

Experts believe that the elderly have a weakened immune system, so they may need twice as much vaccine.

Oxford experts are also considering testing the vaccine in the African country of Kenya, where corona is now growing rapidly.

Why isn't the vaccine being tested by infecting volunteers with corona?
The question has also arisen that if there is a problem with the number of infected people, then as many people as possible should be deliberately infected with corona and then vaccinated.

However, Andrew Pollard says that since there is no proven cure for the corona virus, it is not ethically correct to do so. Then we can test volunteers for the coronavirus to find out how effective the vaccine is.
Is it safe?
Patients participating in the trial have been told that they may experience swelling, headache and fever in the first few days after vaccination, but will be monitored continuously.

Oxford experts say that according to their data, the chances of the patient becoming infected after this vaccine are very low.

It should be noted that the number of corona patients worldwide has reached 2,726,274 while the number of deaths from corona worldwide has reached 191,075. I United States 50,243 deaths, one of deathly country worldwide.

Around the world, 749,752 Corona patients have recovered.

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